반응 #53102

ord-bc36c87058294580a53cfffbd2bc86ad

반응 방정식

CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1cccc(CN2CCOCC2)c1
3-morpholinomethyl-aniline
[Na+].[OH-]
sodium hydroxide
→
O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1cccc(CN2CCOCC2)c1)c1ccccc1
(Z)-3-[1-(3-morpholinomethyl-phenylamino)-1-phenyl-methyli-den]-5-nitro-2-indolinone

반응물

CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1
1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone
Nc1cccc(CN2CCOCC2)c1
3-morpholinomethyl-aniline
[Na+].[OH-]
sodium hydroxide

시약

없음

용매

CN(C)C=O
DMF
CO
methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Prepared analogously to Example 82 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 3-morpholinomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06855710B2uspto-grants-2005_02