반응 #52658
ord-5e8a1e2bb0f9481c9e511871bbe592ce
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타the precipitate which formed
- 2여과was collected by vacuum filtration
- 3세척washed with 50 ml of water
- 4기타dried
실험 절차
A solution of 5-chloroacetyl-2-oxindole (4.18 g) in trifluoroacetic acid (30 ml) was cooled in an ice bath and 4.65 g of triethylsilane added. The mixture was then stirred at room temperature for 3 hours. The mixture was poured into 150 ml of water and the precipitate which formed was collected by vacuum filtration, washed with 50 ml of water and dried to give 2.53 g (65% yield) of 5-(2-chloroethyl)-2-oxindole as a reddish-brown solid.