반응 #526504

반응 방정식

2-Acetamido-5-fluoro-3-nitrobenzoic acid

hydrochloric acid

→

2-amino-5-fluoro-3-nitrobenzoic acid

수율 92.0%

반응 조건

후처리

1. 1
   온도to reflux for 7 hours whereby the solution
2. 2
   기타the precipitate collected
3. 3
   기타dried

실험 절차

2-Acetamido-5-fluoro-3-nitrobenzoic acid (200 mg, 0.83 mmol) was added to 3N hydrochloric acid (4.0 mL) and the solution allowed to reflux for 7 hours whereby the solution contained a bright yellow precipitate. The reaction was cooled to room temperature and the precipitate collected and dried to produce 2-amino-5-fluoro-3-nitrobenzoic acid (152 mg, 92%) as a yellow solid.

출처