반응 #5259

반응 방정식

potassium hydroxide

10-iododecyl allyl ether

methyl p-hydroxybenzoate

potassium carbonate

hydrochloric acid

→

4-(10-allyloxydecyloxy)benzoic acid

수율 80.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타After conclusion of the reaction
2. 2
   기타the acidified reaction solution
3. 3
   농축was then concentrated under reduced pressure
4. 4
   workup.ADDITIONWater was added to the residue
5. 5
   기타to form a suspension
6. 6
   기타the insoluble matter was collected
7. 7
   기타was then dried

실험 절차

70 mmol (22.7 g) of 10-iododecyl allyl ether, 70 mmol (10.6 g) of methyl p-hydroxybenzoate, and 70 mmol (9.6 g) of potassium carbonate were refluxed in absolute ethanol for 15 hours. After addition of an aqueous potassium hydroxide solution (containing 4.0 g of potassium hydroxide) into the reaction solution, the resulting mixture was further heated at 80° C. for 5 hours. After conclusion of the reaction, the reaction solution was acidified with hydrochloric acid, and the acidified reaction solution was then concentrated under reduced pressure. Water was added to the residue to form a suspension, and the insoluble matter was collected and was then dried, to obtain 18.7 g of 4-(10-allyloxydecyloxy)benzoic acid (Yield: 80%).

출처