반응 #5255
ord-332c42f9e23541eaa37b1a643ef16125
반응 방정식
7-amino-cephalosporanic acid
boron trifluoride
propanol
→
3-propoxymethyl-7-amino-ceph-3-eme-4-carboxylic acid
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타were reacted
- 2기타to obtain 17.4 g of raw product which
- 3기타was purified with hot hydrochloric acid and ammonium hydroxide
실험 절차
Using the procedure of Step A of Example 8, 27.2 g of 7-amino-cephalosporanic acid, 170 ml of the etherate of of boron trifluoride, 131 ml of propanol and 128 ml of triethylamine were reacted to obtain 17.4 g of raw product which was purified with hot hydrochloric acid and ammonium hydroxide to obtain 7.45 g of 3-propoxymethyl-7-amino-ceph-3-eme-4-carboxylic acid.