반응 #5254
ord-dcaa90fa626041689c210e2969f0e25b
반응 방정식
7-amino-cephalosporanic acid
boron trifluoride
allyl alcohol
→
3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타were reacted
- 2기타the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide
실험 절차
Using the procedure of Step A of Example 8, 27.2 g of 7-amino-cephalosporanic acid, 170 ml of the etherate of boron trifluoride, 136 ml of allyl alcohol and 115 ml of triethylamine were reacted and the 9 g of raw product was purified successively twice with hot hydrochloric acid and ammonium hydroxide to obtain 4.72 g of 3-allyloxymethyl-7-amino-ceph-3-eme-4-carboxylic acid.