반응 #525118

반응 방정식

hydrochloride

caprolactim 0-methyl ether

4-amino-6-chloro-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene hydrochloride

→

title compound

2-(6-Chloro-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ylimino)hexahydroazepine

용매

ethanol

반응 조건

후처리

1. 1
   기타to stand at room temperature

실험 절차

5 ml of 98% ethanol and 10.0 g of caprolactim 0-methyl ether are added to 8.0 g of 4-amino-6-chloro-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene hydrochloride and are allowed to stand at room temperature while shaking occasionally. A few drops of ether are added to the resulting clear solution after 12 hours, whereupon the hydrochloride of the title compound crystallizes. M.Pt. decomp. from 185°, (recrystallized once from ethanol/ether).

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