반응 #524792

반응 방정식

Crotonyl chloride

2,4-dichloro-6-nitrophenol

→

2,4-dichloro-6-nitrophenyl crotonate

용매

methylene chloride

methylene chloride

반응 조건

후처리

1. 1
   온도the mixture was heated
2. 2
   온도under reflux for 12 hours
3. 3
   추출extracted several times with a 10% sodium hydroxide solution
4. 4
   세척The organic layer was washed with water
5. 5
   건조dried (Na2SO4)
6. 6
   기타the solvent removed under reduced pressure
7. 7
   기타to give a pale brown oil which
8. 8
   기타crystallised

실험 절차

Crotonyl chloride (7 ml) was added to a solution of 2,4-dichloro-6-nitrophenol (10.3 g) in methylene chloride (20 ml) and the mixture was heated under reflux for 12 hours. The solution was diluted with further methylene chloride (200 ml) and extracted several times with a 10% sodium hydroxide solution. The organic layer was washed with water dried (Na2SO4) and the solvent removed under reduced pressure to give a pale brown oil which crystallised on standing for 24 hours 2,4-dichloro-6-nitrophenyl crotonate melted at <60°.

출처