반응 #52198

반응 방정식

4-(2-diethylaminoethoxy)-1-nitrobenzene

→

title compound

수율 46.0%

4-(2-Diethylaminoethoxy)aniline

수율 46.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타The catalyst was removed by filtration through diatomaceous earth
2. 2
   세척the filter pad was washed with methanol
3. 3
   기타The volatiles were removed from the filtrate by evaporation

실험 절차

A mixture of 4-(2-diethylaminoethoxy)-1-nitrobenzene (Method 10) (1.0 g, 4.2 mmol) and 10% palladium on charcoal catalyst (200 mg) in ethanol (30 ml) was stirred under an atmosphere of hydrogen for 3 hours. The catalyst was removed by filtration through diatomaceous earth and the filter pad was washed with methanol. The volatiles were removed from the filtrate by evaporation to give the title compound (400 mg, 46%) as an oil. M/z: 209 [MH]+.

출처