반응 #52154
ord-71916f9f246848959ec6b6ef6ddfd45e
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1농축The reaction mixture was concentrated in vacuo
- 2기타triturated with Et2O (2×70 mL)
- 3기타dried in vacuo
실험 절차
N-BOC-octahydroisoindole-1-carboxylic acid (18.6 mmol) was dissolved in 4 M HCl in dioxane (46.5 mL) at rt. After stirring for 1 hr, the reaction was determined to be complete by TLC. The reaction mixture was concentrated in vacuo, triturated with Et2O (2×70 mL) and then dried in vacuo to afford octahydroisoindole-1-carboxylic acid (4.13 g) as a white solid.