반응 #51970

반응 방정식

4-acetamidoacetophenone

bromine

→

title compound

수율 62.5%

N-[4-(2-bromoacetyl)phenyl]acetamide

수율 62.5%

용매

1,4-dioxane diethyl ether

반응 조건

후처리

1. 1
   여과The solid was collected by filtration
2. 2
   세척washed with diethyl ether
3. 3
   기타dried under high vacuum

실험 절차

To a suspension of 4-acetamidoacetophenone (Lancaster, 5.32 g, 0.03 mol) in 1,4-dioxane/diethyl ether (100 mL, 1:2, v/v) was added bromine (1.53 mL, 0.03 mol) via a syringe. The reaction mixture was stirred at room temperature for 4 hours until the color of the mixture was changed from brown to white. The solid was collected by filtration, washed with diethyl ether, and dried under high vacuum to give the title compound as a white solid (4.8 g).

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