반응 #51850

반응 방정식

1,2-diphenyl-4-(4-methylphenyl)-3,5-pyrazolidinedione

H2O2

Sodium metabisulfite

→

1,2-Diphenyl-4-hydroxy-4-(4-methylphenyl)-3,5-pyrazolidinedione

용매

acetic acid

반응 조건

후처리

1. 1
   기타excess acetic acid evaporated off
2. 2
   workup.DISSOLUTIONThe residue was dissolved in hot ethyl acetate (25 ml)
3. 3
   여과benzene (25 ml) and filtered
4. 4
   온도After cooling to room temperature
5. 5
   여과the mixture was filtered
6. 6
   기타the residue recrystallized from 50% aqueous ethanol (20 ml)
7. 7
   기타to give 0.58 g (53%)

실험 절차

A mixture of 1,2-diphenyl-4-(4-methylphenyl)-3,5-pyrazolidinedione (1.10 g; 3.2 =mol), 35% H2O2 (0.47 ml; 5.5 mmol), and acetic acid (40 ml) was stirred 16 days at room temperature. Sodium metabisulfite (1.0 g) was added and excess acetic acid evaporated off. The residue was dissolved in hot ethyl acetate (25 ml) and benzene (25 ml) and filtered. After cooling to room temperature, the mixture was filtered and the residue recrystallized from 50% aqueous ethanol (20 ml) to give 0.58 g (53%).

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