반응 #51610

반응 방정식

1-(phenylmethyl)-4-piperidinemethanamine

acrylonitrile

→

3-[[[1-(phenylmethyl)-4-piperidinyl]methyl]-amino]-propanenitrile

수율 102.4%

용매

ethanol

반응 조건

후처리

1. 1
   온도refluxed for 4 hours
2. 2
   기타The solvent was evaporated

실험 절차

A mixture of 1-(phenylmethyl)-4-piperidinemethanamine (0.076 mol) and acrylonitrile (0.076 mol) in ethanol (250 ml) was stirred and refluxed for 4 hours. The solvent was evaporated, yielding 20.0 g (102.4%, crude residue, used in next reaction step, without further purification) of 3-[[[1-(phenylmethyl)-4-piperidinyl]methyl]-amino]-propanenitrile (interm. 14).

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