반응 #514215

ord-918f49a5fc4248348d986b175fdd748a

반응 방정식

COC(=O)c1cc(-c2ccccc2)sc1N
Methyl 2-amino-5-phenyl-thiophene-3-carboxylate
O=[N+]([O-])c1cc(F)ccc1F
2,5-difluoronitrobenzene
→
COC(=O)c1cc(-c2ccccc2)sc1Nc1ccc(F)cc1[N+](=O)[O-]
Methyl 2-(4-fluoro-2-nitroanilino)-5-phenyl-thiophene-3-carboxylate

반응물

COC(=O)c1cc(-c2ccccc2)sc1N
Methyl 2-amino-5-phenyl-thiophene-3-carboxylate
O=[N+]([O-])c1cc(F)ccc1F
2,5-difluoronitrobenzene

시약

없음

용매

ClCCl
CH2Cl2

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Methyl 2-amino-5-phenyl-thiophene-3-carboxylate and 2,5-difluoronitrobenzene, m.p. 150° C. (CH2Cl2).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04172831uspto-grants-1979_10