반응 #51409

반응 방정식

L-(+)-ornithine hydrochloride

methanol

→

L-(+)-ornithine methyl ester hydrochloride

수율 97.0%

반응 조건

후처리

1. 1
   기타was bubbled anhydrous hydrochloric acid gas until the solution
2. 2
   기타The reaction mixture was capped with a rubber septum
3. 3
   기타the residue triturated with ether
4. 4
   기타The resulting solid was dried under reduced pressure

실험 절차

Into a stirred suspension of L-(+)-ornithine hydrochloride (Aldrich) in methanol was bubbled anhydrous hydrochloric acid gas until the solution was saturated. The reaction mixture was capped with a rubber septum and stirring was continued overnight at room temperature. The solvent was then stripped under reduced pressure and the residue triturated with ether. The resulting solid was dried under reduced pressure to afford L-(+)-ornithine methyl ester hydrochloride as a white solid (97% yield).

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