반응 #51398

반응 방정식

HCl

5,7-dihydro-6H-dibenzo[a,c]cyclohepten-6-one

butyl nitrite

→

title compound

5-amino-5,7-dihydro-6H-dibenzo[a,c]cyclohepten-6-ol hydrochloride

용매

Et2O

Et2O

반응 조건

후처리

1. 1
   기타prepared
2. 2
   여과After 5 h at 0° C. the resulting precipitate was filtered
3. 3
   세척rinsed with cold Et2O and vacuum
4. 4
   기타dried

실험 절차

A round bottom flask was charged with 5,7-dihydro-6H-dibenzo[a,c]cyclohepten-6-one (1.0 g, 4.81 mmol)(CAS# 1139-82-8, prepared as described in Tetrahedron Letters, Vol. 28, No. 23, (1987). pp 2633-2636) and butyl nitrite (0.673 ml, 5.77 mmol) (Aldrich) in Et2O. The solution was cooled to 0° C. and treated drop-wise with a saturated solution of HCl(g)/Et2O. After 5 h at 0° C. the resulting precipitate was filtered, rinsed with cold Et2O and vacuum dried to give the title compound as a colorless solid.

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