반응 #51334
ord-5197e12bfb334a10b3329c8112e9cee0
반응 방정식
2-aminonaphthalene
ethyl pyruvate
→
title compound
N-(2-naphthyl)alanine ethyl ester
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타Purification
실험 절차
Following reductive amination General Procedure AA above and using 2-aminonaphthalene (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared as a solid having a melting point of 52-56° C. The reaction was monitored by silica gel tlc (Rf=0.50 in 25% EtOAc/hexanes). Purification was by flash chromatography with silica gel using 25% EtOAc/hexanes as the eluant.