반응 #51316

반응 방정식

3,4-dichloroaniline

iso-butyl 2-oxopentanoate

→

title compound

2-[N-(3,4-dichlorophenyl)amino]pentanoic acid iso-butyl ester

반응 조건

후처리

1. 1
   기타The reaction was monitored by tlc on silica gel (Rf=0.5 in 25% EtOAc/hexanes) and purification

실험 절차

Following General Procedure AA above and using 3,4-dichloroaniline (Aldrich) and iso-butyl 2-oxopentanoate (prepared by following General Procedure AO above using 2-oxovaleric acid (Fluka) and iso-butanol), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.5 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).

출처