반응 #51294

반응 방정식

3,5-difluorophenylacetic acid

(S)-2-(1-aminoethyl)-5(R,S)-ethoxycarbonyl-2-oxazoline

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title compound

(S)-2-[1-(3,5-difluorophenylacetamido)ethyl]-5(R,S)-ethoxycarbonyl-2-oxazoline

용매

MeOH CHCl3

반응 조건

후처리

1. 1
   기타the product was purified by silica gel chromatography

실험 절차

Following General Procedure A and using 3,5-difluorophenylacetic acid (Aldrich) and (S)-2-(1-aminoethyl)-5(R,S)-ethoxycarbonyl-2-oxazoline (Example F), the title compound was prepared as a semisolid. The reaction was monitored by tlc (Rf=0.3 in 5% MeOH/CHCl3) and the product was purified by silica gel chromatography using 5% MeOH/CHCl3 as the eluent.

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