반응 #51176

반응 방정식

methyl 1-(3-(hydroxymethyl)phenyl)-5-oxopyrrolidine-3-carboxylate

pyridinium chlorochromate

→

desired product

methyl (3-formylphenyl)-5-oxopyrrolidine-3-carboxylate

용매

CH2Cl2

반응 조건

후처리

1. 1
   여과The mixture was then filtered through a pad of celite
2. 2
   농축The filtrate was concentrated in vacuo

실험 절차

To a solution of methyl 1-(3-(hydroxymethyl)phenyl)-5-oxopyrrolidine-3-carboxylate in CH2Cl2 was added pyridinium chlorochromate (PCC). The reaction was stirred at room temperature overnight. The mixture was then filtered through a pad of celite. The filtrate was concentrated in vacuo and the desired product was obtained after silica gel chromatograph. MS (ES+): 248.0 (M+H)+.

출처