반응 #51112

반응 방정식

Oxalyl chloride

4-pentylbicyclo[2.2.2]octane-1-carboxylic acid

→

4-pentylbicyclo[2.2.2]octane-1-carbonyl chloride

용매

methylene chloride

반응 조건

후처리

1. 1
   농축concentrated in vacuo

실험 절차

Oxalyl chloride (505 μL, 5.79 mmol) was added dropwise to a mixture of 4-pentylbicyclo[2.2.2]octane-1-carboxylic acid (3-A) in methylene chloride (10 mL). The solution was stirred at room temperature for 3 h and then concentrated in vacuo to give 4-pentylbicyclo[2.2.2]octane-1-carbonyl chloride (3-B). 1H NMR (500 MHz, CDCl3): δ 0.90 (t, 3H); 1.21 (m, 8H); 1.45 (m, 6H); 1.88 (m, 6H) ppm.

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