반응 #5096
ord-502e59e83d8340a4bd3c79ffc19efc01
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과filtered
- 2기타to obtain filtrate
- 3세척The Celite used was washed with dichloromethane and ethanol
- 4농축concentrated
- 5기타Recrystallized from dichloromethane-ethanol
실험 절차
5.0 Grams of 4,6-dimethyl-7-hydroxy-2-phenyl-1-indanone was dissolved in 10 ml of diethyl ether and 10 ml of dichloromethane, then this solution was added dropwise gradually to a mixture of a solution of 2.55 ml of benzylamine in 10 ml of diethyl ether with 8 g of Molecular sieves 5A. The whole mixture was stirred at room temperature for 2 days and filtered by using Celite to obtain filtrate. The Celite used was washed with dichloromethane and ethanol, then these washing liquors were combined with the above-mentioned filtrate and concentrated. Recrystallized from dichloromethane-ethanol to obtain 3.83 g of 4,6-dimethyl-7-hydroxy-1-benzylamino-2-phenyl-3H-indene. Orange needle-like crystals.