반응 #50897

반응 방정식

compound 1

2,2,2-Trichloro-1-(4-phenylacetyl-1H-pyrrol-2-yl)-ethanone

benzylamine

→

4-Phenylacetyl-1H-pyrrole-2-carboxylic acid benzylamide

용매

DMF

반응 조건

후처리

1. 1
   기타the solvent was evaporated
2. 2
   기타the crude product 2 was utilized without purification
3. 3
   기타provided a retention time of 3.8 minutes

실험 절차

To a solution of compound 1 (1 equivalent) in DMF, at ambient temperature, was added benzylamine (1.2 equivalents). After 24 hours, the solvent was evaporated and the crude product 2 was utilized without purification. HPLC using method B (as described below for Example 5) provided a retention time of 3.8 minutes. FIA/MS (M+1) 319.3, (M−1) 317.2.

출처