반응 #50763

반응 방정식

6-(3-Pyridyl)-1-hex-5-ynol

ethyl acetate

→

Z-6-(3-pyridyl)-1-hex-5-enol

수율 46.0%

용매

ethanol

반응 조건

후처리

1. 1
   여과The mixture was filtered through celite
2. 2
   기타evaporated
3. 3
   기타to give a clear oil

실험 절차

6-(3-Pyridyl)-1-hex-5-ynol (0.15 g, 0.86 mmol) was added to a stirred suspension of 10% palladium on charcoal (20 mg) in ethanol. The reaction was stirred at room temperature under hydrogen for 24 h. The mixture was filtered through celite and evaporated to give a clear oil. Column chromatography (flash silica gel; ethyl acetate) gave Z-6-(3-pyridyl)-1-hex-5-enol (70 mg, 46%).

출처