반응 #50613

반응 방정식

Fumarate

6-(3-chloropropoxy)-7-methoxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one

1-phenylpiperazine

isopropanol

→

7-methoxy-4-methyl-3-phenyl-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one

수율 66.0%

용매

acetone

반응 조건

후처리

1. 1
   기타Method B (40 h at 50° C.)

실험 절차

Method B (40 h at 50° C.); starting materials: 6-(3-chloropropoxy)-7-methoxy-4-methyl-3-phenyl-2H-1-benzopyran-2-one (example 79) and 1-phenylpiperazine; yield 66%; fusion point 168°-170° C. (from isopropanol). Fumarate: method E; yield 95%; fusion point 219°-221° C. (from acetone).

출처