반응 #5052

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6-[4-(4-(5-aminoindol-3-yl)butyl)piperazino]-1,4-benzodioxane

6-[4-(4-(5-nitroindol-3-yl)butyl)piperazino]-1,4-benzodioxane

acetyl chloride

→

6-[4-(4-(5-Acetamidoindol-3-yl)butyl)piperazino]-1,4-benzodioxane

용매

THF

THF

반응 조건

후처리

1. 1
   기타evaporated

실험 절차

A solution of 4.21 g of 6-[4-(4-(5-aminoindol-3-yl)butyl)piperazino]-1,4-benzodioxane ("C") [obtainable as in Example 5] in 35 ml of THF is treated with a solution of 0.9 g of acetyl chloride in 10 ml of THF, and the mixture is stirred at 50° for 2 hours, evaporated and worked up in the conventional manner. 6-[4-(4-(5-Acetamidoindol-3-yl)butyl)piperazino]-1,4-benzodioxane is obtained.

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