반응 #5045

반응 방정식

Ethyl 4-pyridylacetate

hydrochloric acid

→

ethyl 4-piperidinylacetate

수율 162.3%

용매

ethanol

hydrogen

반응 조건

후처리

1. 1
   여과the contents of the vessel were filtered
2. 2
   농축concentrated in vacuo

실험 절차

16.5 g (0.1 mol) Ethyl 4-pyridylacetate, 8.4 mL (0.1 mol) 12N hydrochloric acid and 2.5 g platinum oxide were dissolved in absolute ethanol and hydrogenated at 40 psi hydrogen on a Parr shaker. After 1 hour, the contents of the vessel were filtered and concentrated in vacuo yielding 27.79 g of ethyl 4-piperidinylacetate.

출처