반응 #50404

반응 방정식

ethyl 3-(2-(4-toluenesulphonylamino)indan-5-yl)-3-(3-pyridyl)-prop-2-enoate

→

3-(2-(4-Toluenesulphonylamino)indan-5-yl)-3-(3-pyridyl)-prop-2-enoic acid

용매

ethanol

—

15N sodium hydroxide

반응 조건

후처리

1. 1
   세척Then the cooled solution is washed 3 times with 50 ml of methylene chloride
2. 2
   기타The precipitate formed
3. 3
   세척is washed
4. 4
   기타dried
5. 5
   기타recrystallised from n-butanol

실험 절차

4.2 g of ethyl 3-(2-(4-toluenesulphonylamino)indan-5-yl)-3-(3-pyridyl)-prop-2-enoate are refluxed for 30 minutes in 40 ml of ethanol and 1.5 ml of 15N sodium hydroxide solution. Then the cooled solution is washed 3 times with 50 ml of methylene chloride and then acidified. The precipitate formed is washed, dried and then recrystallised from n-butanol.

출처