반응 #50375

반응 방정식

hydrochloric acid

sodium hydride

methyl isoferulate

glycidol

→

cinnamic acid

용매

DMSO

반응 조건

후처리

1. 1
   workup.ADDITIONwas added gradually
2. 2
   온도Heating
3. 3
   온도The system was cooled
4. 4
   기타was removed

실험 절차

3 g of methyl isoferulate was dissolved in 600 ml of DMSO, and 370 mg of sodium hydride was added. The system was heated to 90° C. under N2 gas flow and 7 g of glycidol was added gradually. Heating and agitation was carried out for 0.5 hours. The system was cooled, neutralized by adding hydrochloric acid, solvent was removed and adduct of cinnamic acid and glycerin was obtained.

출처