반응 #502147
ord-44a7c2b035cf407bb6b026d354dd1ca4
반응 방정식
2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
pyrrolidine
→
title compound
2-(3-Chlorobenzyl)-6-oxo-4-(1-pyrrolidinyl)-1,6-dihydropyrimidine-5-carbonitrile
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In analogy to the preparation of Example 1, 100 mg (0.34 mmol) of 2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 244 mg (3.43 mmol) of pyrrolidine to give 29 mg (27% of theory) of the title compound.