반응 #502104

반응 방정식

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylamine

2-bromo-1-[1-(phenylsulphonyl)indol-6-yl]ethanone

→

compound

수율 55.5%

2-(1-Phenylsulphonyl-1H-indol-6-yl)-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)imidazo[1,2-a]pyridine hydrobromide

수율 55.5%

용매

ethanol

반응 조건

후처리

1. 1
   온도the mixture is refluxed for 20 h
2. 2
   여과A precipitate forms and is recovered by filtration
3. 3
   세척washed with diethyl ether
4. 4
   기타oven-dried under reduced pressure

실험 절차

1.6 g of 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylamine and 2.7 g of 2-bromo-1-[1-(phenylsulphonyl)indol-6-yl]ethanone are placed in 70 ml of ethanol and the mixture is refluxed for 20 h. A precipitate forms and is recovered by filtration, washed with diethyl ether and oven-dried under reduced pressure. 2.3 g of compound are obtained.

출처