반응 #502054

반응 방정식

chloroacetic acid methylester

3-nitrophenol

DMF

sodium carbonate

→

3-Nitrophenoxyacetic acid methylester

용매

water

반응 조건

후처리

1. 1
   온도After being cooled down to 25° C. it
2. 2
   여과The resulting suspension is filtered off
3. 3
   세척The filter cake is washed with 300 g of water
4. 4
   기타dried in vacuum

실험 절차

300 g of 3-nitrophenol are added to 800 ml of DMF. Then 240 g of sodium carbonate are added portionwise. Subsequently 270 g of chloroacetic acid methylester is added at 22° C. Then the mixture is stirred at 85° C. for six hours. After being cooled down to 25° C. it is given to 3 kg of water and 1 kg of ice. The resulting suspension is filtered off. The filter cake is washed with 300 g of water and dried in vacuum. Yield: 407 g.

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