반응 #50051

ord-7c5c474dbd28494d887887522b80854c

반응 방정식

O=C(O)[C@@H]1CCCN1
L-proline
C[C@@H](N)C(=O)N1CCC[C@@H]1C(=O)O
D-alanyl-D-proline
→
C[C@H](N)C(=O)N1CCC[C@@H]1C(=O)O
L-alanyl-D-proline

반응물

O=C(O)[C@@H]1CCCN1
L-proline
C[C@@H](N)C(=O)N1CCC[C@@H]1C(=O)O
D-alanyl-D-proline

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

By substituting D-proline for L-proline in the above example, a 70% diastereomeric excess mixture of D-alanyl-D-proline and L-alanyl-D-proline was obtained.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05424454uspto-grants-1995_06