반응 #49908

반응 방정식

N'-t-butyl-N,N'-dibenzoylhydrazine

Methoxymethyl chloride

→

N-methoxymethyl-N'-t-butyl-N,N'-dibenzoylhydrazine

용매

toluene

반응 조건

후처리

1. 1
   기타The layers were separated
2. 2
   세척the toluene layer was washed several times with water (until the water washes
3. 3
   건조The toluene solution was dried over anhydrous magnesium sulfate
4. 4
   기타the toluene removed under vacuum

실험 절차

N'-t-butyl-N,N'-dibenzoylhydrazine (2 g, 0.007M) was stirred at room temperature in a two phase system of toluene-50% sodium hydroxide with 100 mg of phase transfer catalyst (tetra-n-butylammonium hydrogen sulfate). Methoxymethyl chloride (1.2 g, 0.015M) was added dropwise and the mixture was stirred 3 hours. The layers were separated and the toluene layer was washed several times with water (until the water washes were neutral). The toluene solution was dried over anhydrous magnesium sulfate and the toluene removed under vacuum to afford N-methoxymethyl-N'-t-butyl-N,N'-dibenzoylhydrazine as a thick oil.

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