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dimethyl acetonedicarboxylate

→

methyl 2,2,4,4-tetramethyl-3,5-dioxohexanecarboxylate

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후처리

1. 1
   기타dimethyl tetra-C-methylacetonedicarboxylate was obtained by methylation

실험 절차

Starting from dimethyl acetonedicarboxylate, dimethyl tetra-C-methylacetonedicarboxylate was obtained by methylation, and this was converted into the dicarboxylic acid methyl ester chloride and then methylated with dimethylcadmium. The methyl 2,2,4,4-tetramethyl-3,5-dioxohexanecarboxylate obtained was cyclized in the presence of sodium methanolate. The total yield (based on dimethyl acetonedicarboxylate) is 0.01% (Chem. Ber. 92, 2033 (1959)).

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