반응 #49831

반응 방정식

pyridinium chlorochromate

(Z)-4-benzyloxy-2-buten-1-ol

Diethyl ether

→

(Z)-4-benzyloxy-2-butenal

수율 65.7%

용매

dichloromethane

반응 조건

후처리

1. 1
   workup.STIRRINGThe mixture was stirred at room temperature for 3 hours
2. 2
   기타insolubles were removed by filtration
3. 3
   workup.DISTILLATIONThe filtrate was distilled under reduced pressure
4. 4
   기타to remove the solvent
5. 5
   기타the residue was purified by silica gel column chromatography (diethyl ether)

실험 절차

11.1 g of pyridinium chlorochromate and 12 g of Celite were suspended in 100 ml of dry dichloromethane, and 6 g of (Z)-4-benzyloxy-2-buten-1-ol was added thereto at 0° C. under stirring. The mixture was stirred at room temperature for 3 hours. Diethyl ether was added thereto, and insolubles were removed by filtration. The filtrate was distilled under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography (diethyl ether) to obtain 3.9 g of (Z)-4-benzyloxy-2-butenal as slightly yellow oily substance.

출처