반응 #49711

반응 방정식

methyl 4-hydroxybenzoate

octadecylbromide

potassium carbonate

→

methyl 4-octadecyloxybenzoate

수율 45.4%

용매

2-butanone

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도at reflux for 16 hours
3. 3
   기타The solvent was then removed until 125 ml of 2-butanone
4. 4
   기타had been collected
5. 5
   온도While it was still warm
6. 6
   workup.ADDITIONthe remaining material was poured into methanol (400 ml)
7. 7
   여과The product was filtered
8. 8
   기타recrystallized from 2000 ml of methanol

실험 절차

A mixture containing methyl 4-hydroxybenzoate (45.6 g), octadecylbromide (100 g), and potassium carbonate (41.4 g) in 2-butanone (200 ml) was heated at reflux for 16 hours. The solvent was then removed until 125 ml of 2-butanone had been collected. While it was still warm, the remaining material was poured into methanol (400 ml). The product was filtered and recrystallized from 2000 ml of methanol to give methyl 4-octadecyloxybenzoate (55 g).

출처