반응 #495241

반응 방정식

Metformin hydrochloride

metformin hydrochloride

magnesium stearate

→

Metformin

용매

water

반응 조건

후처리

1. 1
   기타dried in the same device
2. 2
   기타Dried granulate
3. 3
   기타Obtained granulate
4. 4
   기타is obtained

실험 절차

Metformin hydrochloride is screened through 1 mm sieve. Screened metformin hydrochloride and hydroxypropylmethylcellulose are granulated in fluid bed granulator with demineralized water and dried in the same device. Dried granulate is screened through 1 mm sieve. Obtained granulate and microcrystalline cellulose are homogenously blended in a bin blender. Pre-sieved magnesium stearate is added to the obtained blend and blended in a bin blender so that the final blend is obtained.

출처