반응 #49430
ord-9a169952625b44f78af215c66640ebdc
반응 방정식
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In a similar manner to Step 1 of Example 233, 4-hydroxy-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone (0.0289 g, 0.0626 mmol) was dissolved in acetonitrile (0.650 mL), and the solution was treated with triethylamine (0.0540 mL, 0.390 mmol) and 2,4-dimethoxybenzenesulfonyl chloride (0.0462 g, 0.195 mmol) to obtain 4-(2,4-dimethoxybenzenesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone (0.0117 g, yield 20%).