반응 #493185

반응 방정식

water

tert-butyl-chloro-dimethyl-silane

imidazole

3-benzyloxy-phenol

→

(3-Benzyloxy-phenoxy)-tert-butyl-dimethyl-silane

용매

THF

반응 조건

후처리

1. 1
   추출the mixture was then extracted with methylene chloride
2. 2
   추출The organic phase was extracted three times with water
3. 3
   건조dried over sodium sulfate
4. 4
   농축concentrated in vacuo
5. 5
   여과filtered over Alox (neutral)
6. 6
   농축concentrated

실험 절차

43.459 ml tert-butyl-chloro-dimethyl-silane were added at rt to a solution of 17 g imidazole and 25 g 3-benzyloxy-phenol in 400 ml THF. After 3 hours water was added to the reaction mixture and the mixture was then extracted with methylene chloride. The organic phase was extracted three times with water, dried over sodium sulfate and concentrated in vacuo. The residue was solved in methylene chloride and filtered over Alox (neutral) and concentrated.

출처