반응 #49078

반응 방정식

D1

1-(dimethylamino)cyclopentanecarbonitrile

dimethylamine hydrochloride

3-pentanone

potassium cyanide

→

title compound

수율 57.5%

2-(Dimethylamino)-2-ethylbutanenitrile

수율 57.5%

용매

water

반응 조건

실험 절차

The title compound (8.05 g, 57.5%) was prepared from dimethylamine hydrochloride (8.154 g, 0.1 mol), 3-pentanone (8.61 g, 0.1 mol) and potassium cyanide (6.51 g, 0.1 mol) in water (50 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 0.96 (6H, t, J=7.6 Hz), 1.67-1.90 (4H, m), 2.33 (6H, s).

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