반응 #49076

반응 방정식

D4

2-methyl-2-(1-pyrrolidinyl)propanenitrile

pyrrolidine

3-pentanone

potassium cyanide

→

title compound

수율 100.0%

2-Ethyl-2-(1-pyrrolidinyl)butanenitrile

수율 100.0%

용매

water

반응 조건

실험 절차

The title compound (8.8 g, 100%) was prepared from pyrrolidine (8.96 ml, 0.107 mol), 3-pentanone (8.61 g, 0.1 mol) and potassium cyanide (6.51 g, 0.1 mol) in water (50 ml) in a similar manner to that described in D4. 1H NMR (CDCl3) δ: 0.95 (6H, t, J=7.6 Hz), 1.67-1.90 (8H, m), 2.67-2.72 (4H, m).

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