반응 #4856

반응 방정식

2-(2-amino-3,5-dinitrophenyl)ethanol

sodium sulphide nonahydrate

sulphur

→

expected product

2-(2,3-diamino-5-nitrophenyl)ethanol

용매

isopropanol

water

water

반응 조건

후처리

1. 1
   workup.ADDITIONhas been added
2. 2
   온도Heating
3. 3
   온도is maintained for 20 minutes
4. 4
   workup.ADDITIONafter the addition
5. 5
   온도When the mixture is cooled

실험 절차

To a suspension of 0.119 mole (27 g) of 2-(2-amino-3,5-dinitrophenyl)ethanol obtained in Example 1 in 67.5 ml of isopropanol to which an equal volume of water has been added, a solutionof 38.4 g of sodium sulphide nonahydrate and 5.4 g of sulphur in 10 ml of water is added dropwise at 60°-65° C. Heating is maintained for 20 minutes after the addition is complete. When the mixture is cooled, a precipitate of the expected product is obtained, and this is drained, made into a paste in water and then recrystallized from 96° strength alcohol. It melts at 172° C.

출처