반응 #48552

반응 방정식

4-chlorophenyl isothiocyanate

ethyl isonipecotate

→

title compound

Ethyl 1-{[(4-chlorophenyl)amino]carbonothioyl}piperidine-4-carboxylate

용매

dichloromethane

반응 조건

후처리

1. 1
   농축The mixture was concentrated under reduced pressure
2. 2
   기타the residue was triturated with ether
3. 3
   여과the resulting solid was filtered off
4. 4
   기타dried

실험 절차

A mixture of 4-chlorophenyl isothiocyanate (3.5 g, 20.7 mmol), and ethyl isonipecotate (3.19 mL, 20.7 mmol) in dichloromethane (30 mL) was stirred at room temperature for 1 hour. The mixture was concentrated under reduced pressure, the residue was triturated with ether and the resulting solid was filtered off and dried to afford the title compound as a white solid, 6.27 g.

출처