반응 #4855

반응 방정식

2,3-dihydro-5,7-dinitro-2-methyl-benzofuran

methylamine

→

1-(2-methylamino-3,5-dinitrophenyl)-2-propanol

용매

ethanol

반응 조건

후처리

1. 1
   온도After the mixture is cooled
2. 2
   기타the expected product precipitates
3. 3
   세척washed with alcohol
4. 4
   기타recrystallized from 50 ml of 96° strength ethanol
5. 5
   기타After being dried
6. 6
   기타0.047 mole (12 g) is obtained of a product which melts at 132° C.

실험 절차

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

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