반응 #48308

반응 방정식

(R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate

2,4-dichlorothiazole

→

title compound

(S)-methyl 2-(tert-butoxycarbonyl)-3-(4-chlorothiazol-2-yl)propanoate

반응 조건

후처리

1. 1
   기타prepared
2. 2
   기타New synthesis of the thiazole ring

실험 절차

The title compound was synthesized in a manner analogous to that described Example 475, using (R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate and 2,4-dichlorothiazole (prepared according to Reynaud, Pierre; Robba, Max; Moreau, Robert C; New synthesis of the thiazole ring; Bulletin de la Societe Chimique de France (1962), 1735-8). MS m/z: 321 (23%, M+1), 265.0 (100%, M−55.1).

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