반응 #482535

반응 방정식

2,6-Dinitrobenzenecarbonitrile

ethylpiperazine

H2O

→

desired product

2-(4-Ethylpiperazinyl)-6-nitrobenzenecarbonitrile

용매

DMF

반응 조건

후처리

1. 1
   온도The solution was cooled to room temperature
2. 2
   기타A precipitate formed which
3. 3
   여과was filtered

실험 절차

2,6-Dinitrobenzenecarbonitrile (1.0 eq) and ethylpiperazine (3.6 eq) were dissolved in DMF. The resulting solution heated at 90° C. for 2 hours. The solution was cooled to room temperature and poured into H2O. A precipitate formed which was filtered to yield the desired product as a brown solid. LC/MS m/z260.1 (MH+), Rf 1.69 minutes. 6-Amino-2-(4-ethylpiperazinyl)benzenecarbonitrile

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