반응 #481605

반응 방정식

3,5-Dimethoxy-4-hydroxy benzaldehyde

ethyl acetoacetate

piperidine—acetic acid

→

title product

Ethyl-alpha-acetyl-3,5-dimethoxy-4-hydroxy-cinnamate

용매

benzene

반응 조건

후처리

1. 1
   온도at reflux temperature

실험 절차

Monodemethylation of 3,4,5-trimethoxy benzaldehyde using sulphuric acid at 40° C. for 8 hours as described above in Example 1 yields syringaldehyde. Condensation of 3,5-Dimethoxy-4-hydroxy benzaldehyde (syringaldehyde) with ethyl acetoacetate in the presence of piperidine—acetic acid and benzene as the reaction medium at reflux temperature yields the title product. The reaction takes about 3.5 hours for completion.

출처