반응 #481601

반응 방정식

3,4,5-trimethoxybenzaldehyde

sulphuric acid

→

syringaldehyde

반응 조건

후처리

1. 1
   기타at 40° C.
2. 2
   기타for 8 hours

실험 절차

Monodemethylation of 3,4,5-trimethoxybenzaldehyde using sulphuric acid at 40° C. for 8 hours as described above in Example 1 yields syringaldehyde. Condensation of 3,5-Dimethoxy-4-hydroxy benzaldehyde (Syringaldehyde) with diethyl malonate in the presence of piperidine—acetic acid and benzene as the reaction medium at reflux temperature under continuous azeotropic water removal yields the title product. The reaction takes about 7.5 hours for completion.

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