반응 #48109

ord-087999f7e0d549caa6d74fe79b97b3d8

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

In a departure from the procedure described above the compound is prepared from 4-difluoromethyl-1-iodo-benzene (prepared from 4-iodobenzaldehyde using diethylaminosulfurtrifluoride (DAST) in dichloromethane) using iPrMgCl to generate the arylmetal compound and trapping this intermediate with trimethyl borate.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07745414B2uspto-grants-2010_06